Nano-Hydroxyapatite (Nano-HAp) has recently become a popular talking point in dental care as an alternative to fluoride in toothpaste. It can be difficult to find the right toothpaste for you and your dental needs. With such a variety available, it is important to understand what the best ingredients are for maintaining and improving your teeth.

What is Nano-Hydroxyapatite?

Hydroxyapatite is a calcium phosphorus compound, which can be found in our teeth, bones, and saliva. Fun fact– over 97% of our teeth are made up of this mineral! 

Nano-HAp is the synthetic version, formulated to be used in medical and dental care.

What does it do?

Hydroxyapatite was first used for medical purposes by NASA in 1970 to help repair and remineralise astronauts’ teeth after they had returned from space with significant enamel loss. Remineralisation is the process of filling in micro cracks and damage in enamel. In 1978, a Japanese company, Sangi Co Ltd, acquired the patent and it is now a popular ingredient in Japan’s dental products for decay prevention.

Nano-HAp toothpaste has been proven to rebuild areas where cavities have begun developing. It also can help smooth the surface of enamel and aids in long-term tooth decay prevention.

Benefits for teeth

There are several benefits to using Nano-HAp, including reductions in:

  • Temperature sensitivity
  • Plaque build-up
  • Oral bacteria
  • Gum irritation– caused by gingivitis

For those more sensitive to fluoride, such as pregnant women, young children, or those at higher risk of dental fluorosis, this is a great alternative ingredient for toothpaste!

Is it better than Fluoride?

Research has shown the two ingredients are comparable in their ability to remineralise teeth enamel! 

The biggest difference between the two is fluoride restores enamel through using our saliva, and Nano-HAp works by focusing on the minerals in our teeth. Whilst Nano-HAp helps to protect and strengthen teeth at a deep level, it is more vulnerable to acidity.

Unlike fluoride, which carries a small risk of Dental Fluorosis when children ingest large amounts, Nano-HAp has not been found to have similar effects. Some prefer to take Nano-HAp as a supplement, however, there can be side effects, such as dry mouth, headaches, and stomach discomfort. 


Toothpaste with both fluoride and Nano-HAp are available for those wanting to boost their dental care routine. It’s important to note that it can be more expensive than standard fluoride toothpaste.

If you are more sensitive or at risk to fluoride, Nano-HAp toothpaste is our favoured alternative. 

At Australia Fair Dental Clinic, we are here to help you maintain your very best smile. From choosing the right toothpaste to root canal treatment and more, our team are here to make the journey as relaxing and informative as possible.